Autoimmune Positive Controls

HAP-0600

Product Name:  Bulk Pack of Positive Control Sera: Ro/SS-A, La/SS-B, Sm, RNP, Scl-70, and Jo-1

Designed with the researcher in mind, ImmunoVision has assembled a special package containing 2 ml each of our human control sera for Scl-70, Sm, nRNP, Jo-1, Ro/SS-A, and La/SS-B. FOR ACTIVITY OF EACH HUMAN ANTIBODY, PLEASE REFER TO THE INDIVIDUAL PRODUCTS.

Specificity

For the specificity of each human antibody, please refer to the individual products.

Product Code
CodeAmountPrice
HAP-06006 x 2 ml$792.00
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized Water per vial. After reconstituting, aliquot and store frozen at -20°C.

Specifications

HCL-0100

Human Antibody Against Cardiolipin Antigen

This product has high IgG Anti-Cardiolipin activity. The titer obtained will vary with the test system.

Specificity

The specificity is verified by using a standardized ELISA protocol. This product shows no reactivity at a dilution of 1:100 when tested against purified Ro/SS-A, La/SS-B, Sm, Scl-70, nRNP, Mitochondrial, or Ribosomal P antigens in an ELISA system designed to detect IgG antibody.

Product Code
CodeAmountPrice
HCL-01002 ml$130.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HCT-0100

Human Antibody Against Centromere

Titer is between 1:1000 and 1:5000 ANA by IFA.

Specificity

Single donor human plasma is delipidized and defibrinated, then the immunoglobulin fraction is precipitated and collected. Antibody concentration is adjusted for consistent lot to lot titer.

Product Code
CodeAmountPrice
HCL-01002 ml$130.80
Physical State

Lyophilized Powder

Buffer

0.01M phosphate, 0.13 M NaCl, 0.02% NaN3.

Preservative

0.02% NaN3

Reconstitute

Reconstitute with 2 ml deionized H2O.    Aliquot and store at < 0 ºC

Specifications
Certificate of Analysis

HDD-0100

Product Name:   Human Antibody Against dsDNA Antigen

This product has only the Anti-dsDNA activity when tested by ELISA. The titer obtained will vary with the test with the test system.

Specificity

The specificity is verified by ELISA and radio-immunoassay. This product shows no reactivity at a dilution of 1:100 when tested against purified Ro/SS-A, La/SS-B, Sm, nRNP, Scl-70, ssDNA, and Jo-1 antigens in an ELISA system designed to detect IgG antibody. This product is negative for anti-ssDNA in a radio-immunoassay.

Product Code
CodeAmountPrice
HDD-01002 ml130.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% NaN3

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HIS-0100

Product Name:  Human Antibody Against Whole Histones

Human autoantibody against whole histones. Single donor human plasma is delipidized and defibrinated, then the immunoglobulin fraction is precipitated and collected. Antibody concentration is adjusted for consistent lot to lot titer.

Specificity

Human autoantibody against whole histones, buffered with 0.01M phosphate, 0.13 M NaCl, 0.02% NaN3. Shows anti-histone activity when tested by ELISA techniques using purified histones. Any reactivity with other autoantigens is indicated on the Certificate of Analysis.

Product Code
CodeAmountPrice
HIS-01002 ml$130.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.    After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HJO-0100

Product Name:   Human Antibody Against Jo-1 Antigen

This product has only the Anti-Jo-1 precipitin band when tested using double immunodiffusion against rabbit thymus extract. The titer obtained will vary with the test system; however, undiluted antibody shows a strong Anti-Jo-1 precipitin band.

Specificity

The specificity is verified by a precipitin line of identity with the CDC-AF reference serum. This product shows no reactivity at a dilution of 1:100 when tested against purified nRNP, Ro/SS-A, La/SS-B, Scl-70, Sm, Mitochondrial, or Ribosomal P antigens in an ELISA system designed to detect IgG antibody.

Product Code
CodeAmountPrice
HJO-01002 ml$196.80
Physical State

Lyophilized Powder

Buffer

Buffer:0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HMP-0100

Product Name:   Human Antibody Against MPO Antigen

This product has antibodies to Myeloperoxidase and exhibits a P-ANCA pattern by IFA

Specificity

The specificity is verified by immunofluorescence and ELISA. This product shows no reactivity at a dilution of 1:100 when tested against purified PR-3, Ro/SS-A, La/SS-B, Sm, nRNP, Scl-70, and Jo-1 antigens in an ELISA system designed to detect IgG antibody.

Product Code
CodeAmountPrice
HMP-01002 ml$130.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HMS-0100

Product Name:  Human Antibody Against Mitochondrial Antigen

This product has only the Anti-Mitochondrial fluorescent pattern. The titer obtained will vary with the test system; however, a 1:100 dilution of antibody shows a strong Anti-Mitochondrial fluorescent pattern.

Specificity

This product shows no reactivity at a dilution of 1:100 when tested against purified nRNP, Ro/SS-A, La/SS-B, Scl-70, Sm, Jo-1, and Ribosomal P antigens in an ELISA system designed to detect IgG antibody.

Product Code
CodeAmountPrice
HMS-01002 ml$130.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HNP-0100

Product Name:   Human Normal Serum

Specificity

Single donor normal human plasma is delipidized and defibrinated, then the immunoglobulin fraction is precipitated and collected.

Product Code
CodeAmountPrice
HNP-01002 ml$66.00
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C.

Specifications

HPO-0100

Product Name:  Human Antibody Against Ribosomal P Antigen

This product has only the Anti-Ribosomal P precipitin band when tested using double immunodiffusion against rabbit thymus extract. The titer obtained will vary with the test system; however, undiluted antibody shows a strong Anti-P precipitin band.

Specificity

Specificity has been established by the formation of a precipitin line of identity with a standard reference serum. This product shows no reactivity at a dilution of 1:100 when tested against purified nRNP, Ro/SS-A, La/SS-B, Scl-70, Sm, Jo-1, or Mitochondrial antigens in an ELISA system designed to detect IgG antibody.

Product Code
CodeAmountPrice
HPO-01002 ml$130.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water. After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HPR-0100

Product Name:   Human Antibody Against PR-3 Antigen

This product has antibodies to Proteinase 3 and exhibits a C-ANCA pattern by IFA.

Specificity

The specificity is verified by indirect immunofluorescence and ELISA. This product shows no reactivity at a dilution of 1:100 when tested against purified MPO, nRNP, Ro/ SS-A, La/SS-B, Scl-70, Jo-1, Mitochondrial, or Ribosomal antigens in an ELISA system designed to detect IgG antibody classes.

Product Code
CodeAmountPrice
HPR-01002 ml$196.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HRN-0100

Product Name:   Human Antibody Against RNP Antigen

This product has only the Anti-nRNP precipitin band when tested using double immunodiffusion against rabbit thymus extract. The titer obtained will vary with the test system; however, undiluted antibody shows a strong Anti-nRNP precipitin band.

Specificity

The specificity is verified by a precipitin line of identity with the CDC-AF reference serum. This product shows no reactivity at a dilution of 1:100 when tested against purified Ro/SS-A, La/SS-B, Scl-70, Jo-1, Mitochondrial, or Ribosomal P antigens in an ELISA system designed to detect IgG antibody.

Product Code
CodeAmountPrice
HRN-01002 ml$130.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C.

Specifications
Certificate of Analysis

HSA-0100

Product Name:   Human Antibody Against Ro/SS-A

This product has only the Anti-Ro/SS-A precipitin band when tested using double immunodiffusion against primate spleen extract or calf spleen extract. The titer obtained will vary with the test system; however, undiluted antibody shows a strong Anti-Ro/SS-A precipitin band.

Specificity

The specificity is verified by a precipitin line of identity with the CDC-AF reference serum. This product shows no reactivity at a dilution of 1:100 when tested against purified Sm, nRNP, La/SS-B, Scl-70, Jo-1, Mitochondrial, or Ribosomal P antigens in an ELISA system designed to detect IgG antibody. These sera are powerfully positive in an AntiRo/SS-A ELISA system.

Product Code
CodeAmountPrice
HSA-01002 ml$130.80
Physical State

Lyophilized Powder

Buffer

0.01M Phosphate, 0.13M NaCl, 0.02% Azide

Preservative

0.02% Azide

Reconstitute

2 ml Deionized water.   After reconstituting, aliquot and store frozen at -20°C

Specifications
Certificate of Analysis